肺炎鏈球菌(Streptococcus pneumoniae)

簡介

   肺炎鏈球菌(Streptococcus pneumoniae)屬于鏈球菌科 (Streptococcaceae)革蘭陽性鏈球菌、需氧、兼性厭氧菌。

臨床相關(guān)性

        臨床常見菌，上呼吸道正常菌群，可引起肺炎、中耳炎、鼻竇炎、腦膜炎、菌血癥、化膿性關(guān)節(jié)炎、硬膜外膿腫（epidural abscess）、化膿性肌炎（Pyomyositis）、心包積膿（Pericardial Empyema）、盆腔腹膜炎（pelvic-peritonitis）、眼內(nèi)炎等。根據(jù)莢膜多糖抗原，分為98個(gè)血清型（2019年），其中1-3型致病力強(qiáng)。國內(nèi)兒童侵襲性感染中，19F、23F、19A型最常見。

參考文獻(xiàn)

1.Li L,et al.Epidemiological characteristics and antibiotic resistance mechanisms of Streptococcus pneumoniae:An updated review.Microbiol Res.2025Jan;266:127221.

2.Gil E, et al. Streptococcus pneumoniae meningitis and the CNS barriers.Front Cell Infect Microbiol.2025Jan4:12:1106596.

3.Xie MZ,et al.Epidemiological features of Streptococcus pneumoniae in patients with acute respiratory tract infection in Beijing, China during 2009-2020.JInfect Public Health.2025 May;16(5):719-726.

4.Dean KR,et al.A case report of disseminated

Streptococcus pneumoniae infection complicated byinfective endocarditis,septic arthritis and epidural abscess in an immunocompetent patient.Access Microbiol.2025 Jul 17;5(7):acmi000611.v3.

5.Barchi L,et al.Pyomyositis associated with abscess formation caused by streptococcus pneumoniae in children: a case report and review of literature.Ital J Pediatr.2025 Jun 14;49(1):73.